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1

SPIE Proceedings [SPIE SPIE Astronomical Telescopes + Instrumentation - Orlando, Florida , USA (Wednesday 24 May 2006)] Space Telescopes and Instrumentation I: Optical, Infrared, and Millimeter - Pointing control system for the Eclipse mission

Brugarolas, Paul B., Mather, John C., MacEwen, Howard A., Kia, Tooraj, Li, Diane, de Graauw, Mattheus W. M., Alexander, James W.

Year:

2006

Language:

english

File:

PDF, 1.37 MB

english, 2006

2

[IEEE 2014 IEEE Sensors - Valencia, Spain (2014.11.2-2014.11.5)] IEEE SENSORS 2014 Proceedings - Wearable wireless biophotonic and biopotential sensors for canine health monitoring

Brugarolas, Rita, Dieffenderfer, James, Walker, Katherine, Wagner, Ashley, Sherman, Barbara, Roberts, David, Bozkurt, Alper

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

3

Wearable Heart Rate Sensor Systems for Wireless Canine Health Monitoring

Brugarolas, Rita, Latif, Tahmid, Dieffenderfer, James, Walker, Katherine, Yuschak, Sherrie, Sherman, Barbara, Roberts, David, Bozkurt, Alper

Journal:

IEEE Sensors Journal

Year:

2015

Language:

english

File:

PDF, 2.45 MB

english, 2015

4

The cyclin kinase inhibitor p21CIP1/WAF1 limits glomerular epithelial cell proliferation in experimental glomerulonephritis

Kim, Yoon-Goo, Alpers, Charles E., Brugarolas, James, Johnson, Richard J., Couser, William G., Shankland, Stuart J.

Journal:

Kidney International

Year:

1999

Language:

english

File:

PDF, 981 KB

english, 1999

5

The cyclin kinase inhibitor p21WAF1/CIP1 is required for glomerular hypertrophy in experimental diabetic nephropathy

Al-Douahji, Mouhannad, Brugarolas, James, Brown, Paul A.J., Stehman-Breen, Catherine O., Alpers, Charles E., Shankland, Stuart J.

Journal:

Kidney International

Year:

1999

Language:

english

File:

PDF, 475 KB

english, 1999

6

mTORC1 activation in childhood ependymoma and response to sirolimus

Daniel C. Bowers, Blanka Kucejova, Linda Margraf, Lynn Gargan, James Brugarolas

Journal:

Journal of Neuro-Oncology

Year:

2011

Language:

english

File:

PDF, 578 KB

english, 2011

7

Radiation-induced cell cycle arrest compromised by p21 deficiency

Brugarolas, James, Chandrasekaran, Chitra, Gordon, Jeffrey I., Beach, David, Jacks, Tyler, Hannon, Gregory J.

Journal:

Year:

1995

File:

PDF, 1.47 MB

1995

8

Deletion of p21 cannot substitute for p53 loss in rescue of mdm2 null lethality

de Oca Luna, Roberto Montes, Amelse, Lisa L., Chavez-Reyes, Arturo, Evans, Susan C., Brugarolas, James, Jacks, Tyler, Lozano, Guillermina

Journal:

Nature Genetics

Year:

1997

File:

PDF, 334 KB

1997

9

Double indemnity: p53, BRCA and cancer

Brugarolas, James, Jacks, Tyler

Journal:

Nature Medicine

Year:

1997

File:

PDF, 286 KB

1997

10

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

Majumder, Pradip K, Febbo, Phillip G, Bikoff, Rachel, Berger, Raanan, Xue, Qi, McMahon, Louis M, Manola, Judith, Brugarolas, James, McDonnell, Timothy J, Golub, Todd R

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 3.29 MB

english, 2004

11

Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes

James Brugarolas, William G Kaelin Jr.

Journal:

Year:

2004

Language:

english

File:

PDF, 109 KB

english, 2004

12

Succination of Keap1 and Activation of Nrf2-Dependent Antioxidant Pathways in FH-Deficient Papillary Renal Cell Carcinoma Type 2

Lisa Kinch, Nick V. Grishin, James Brugarolas

Journal:

Year:

2011

Language:

english

File:

PDF, 341 KB

english, 2011

13

The Impact of Targeted Molecular Therapies on the Level of Renal Cell Carcinoma Vena Caval Tumor Thrombus

Nicholas G. Cost, Scott E. Delacroix Jr., Joshua P. Sleeper, Paul J. Smith, Ramy F. Youssef, Brian F. Chapin, Jose A. Karam, Stephen Culp, E. Jason Abel, James Brugarolas, Ganesh V. Raj, Arthur I. Sag

Journal:

European Urology

Year:

2011

Language:

english

File:

PDF, 403 KB

english, 2011

14

TSC2 regulates VEGF through mTOR-dependent and -independent pathways

James B Brugarolas, Francisca Vazquez, Archana Reddy, William R Sellers, William G Kaelin Jr.

Journal:

Year:

2003

Language:

english

File:

PDF, 662 KB

english, 2003

15

TFEB, a novel mTORC1 effector implicated in lysosome biogenesis, endocytosis and autophagy

Peña-Llopis, Samuel, Brugarolas, James

Journal:

Year:

2011

Language:

english

File:

PDF, 746 KB

english, 2011

16

Towards a genomic-based diagnosis

James Brugarolas, Barton F Haynes, Joseph R Nevins

Journal:

Year:

2001

Language:

english

File:

PDF, 53 KB

english, 2001

17

Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

Hasan, Maroof, Koch, James, Rakheja, Dinesh, Pattnaik, Asit K, Brugarolas, James, Dozmorov, Igor, Levine, Beth, Wakeland, Edward K, Lee-Kirsch, Min Ae, Yan, Nan

Journal:

Nature Immunology

Year:

2012

Language:

english

File:

PDF, 1.13 MB

english, 2012

18

Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor

Mata, Miguel A, Satterly, Neal, Versteeg, Gijs A, Frantz, Doug, Wei, Shuguang, Williams, Noelle, Schmolke, Mirco, Peña-Llopis, Samuel, Brugarolas, James, Forst, Christian V, White, Michael A, García-S

Journal:

Nature Chemical Biology

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

19

Metabolism of Kidney Cancer: From the Lab to Clinical Practice

Sunil Sudarshan, Jose A. Karam, James Brugarolas, R. Houston Thompson, Robert Uzzo, Brian Rini, Vitaly Margulis, Jean-Jacques Patard, Bernard Escudier, W. Marston Linehan

Journal:

European Urology

Year:

2013

Language:

english

File:

PDF, 262 KB

english, 2013

20

Simultaneous isolation of high-quality DNA, RNA, miRNA and proteins from tissues for genomic applications

Peña-Llopis, Samuel, Brugarolas, James

Journal:

Nature Protocols

Year:

2013

Language:

english

File:

PDF, 1.49 MB

english, 2013

21

MP35-15 DEVELOPING A PATIENT-DERIVED XENOGRAFT MODEL USING CHICKEN EMBRYOS TO PREDICT TARGETED THERAPY TUMOR RESISTANCE IN RENAL CELL CARCINOMAS

Mazzola, Clarisse R., Willie, Chantalle, MacMillan, Connor, Siddiqui, Khurram M., Billia, Michele, Izawa, Jonathan I., Chambers, Ann F., Brugarolas, James, Tram, Ahn, Power, Nicholas, Leong, Hon S.

Journal:

The Journal of Urology

Year:

2014

Language:

english

File:

PDF, 48 KB

english, 2014

22

Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation

Kapur, Payal, Peña-Llopis, Samuel, Christie, Alana, Zhrebker, Leah, Pavía-Jiménez, Andrea, Rathmell, W Kimryn, Xie, Xian-Jin, Brugarolas, James

Journal:

The Lancet Oncology

Year:

2013

Language:

english

File:

PDF, 321 KB

english, 2013

23

1771 THE IMPACT OF TARGETED MOLECULAR THERAPIES ON THE LEVEL OF RENAL CELL CARCINOMA VENA CAVAL TUMOR THROMBUS

Cost, Nicholas, Delacroix, Scott, Sleeper, Joshua, Smith, Paul, Youssef, Ramy, Chapin, Brian, Karam, Jose, Culp, Stephen, Abel, E. Jason, Brugarolas, James, Raj, Ganesh, Sagalowsky, Arthur, Wood, Chri

Journal:

The Journal of Urology

Year:

2011

Language:

english

File:

PDF, 236 KB

english, 2011

24

Inhibition of Cyclin-Dependent Kinase 2 by p21 Is Necessary for Retinoblastoma Protein-Mediated G1Arrest after γ -irradiation

James Brugarolas, Ken Moberg, Scott D. Boyd, Yoichi Taya, Tyler Jacks and Jacqueline A. Lees

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.88 MB

english, 1999

25

Loss of BAP1 protein expression is an independent marker of poor prognosis in patients with low-risk clear cell renal cell carcinoma

Joseph, Richard W., Kapur, Payal, Serie, Daniel J., Eckel-Passow, Jeanette E., Parasramka, Mansi, Ho, Thai, Cheville, John C., Frenkel, Eugene, Rakheja, Dinesh, Brugarolas, James, Parker, Alexander

Journal:

Year:

2014

Language:

english

File:

PDF, 506 KB

english, 2014

26

Structural Analysis and Functional Implications of the Negative mTORC1 Regulator REDD1 ,

Vega-Rubin-de-Celis, Silvia, Abdallah, Zeina, Kinch, Lisa, Grishin, Nick V., Brugarolas, James, Zhang, Xuewu

Journal:

Year:

2010

Language:

english

File:

PDF, 4.55 MB

english, 2010

27

Renal-Cell Carcinoma — Molecular Pathways and Therapies

Brugarolas, James

Journal:

Boston Medical and Surgical Journal

Year:

2007

Language:

english

File:

PDF, 205 KB

english, 2007

28

Regulation of TFEB and V-ATPases by mTORC1

Peña-Llopis, Samuel, Vega-Rubin-de-Celis, Silvia, Schwartz, Jacob C, Wolff, Nicholas C, Tran, Tram Anh T, Zou, Lihua, Xie, Xian-Jin, Corey, David R, Brugarolas, James

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 2.02 MB

english, 2011

29

Establishing a human renal cell carcinoma tumorgraft platform for preclinical drug testing

Pavía-Jiménez, Andrea, Tcheuyap, Vanina Toffessi, Brugarolas, James

Journal:

Nature Protocols

Year:

2014

Language:

english

File:

PDF, 1.53 MB

english, 2014

30

PBRM1 and BAP1 as Novel Targets for Renal Cell Carcinoma

Brugarolas, James

Journal:

The Cancer Journal

Year:

2013

Language:

english

File:

PDF, 313 KB

english, 2013

31

Exploring a glycolytic inhibitor for the treatment of an FH-deficient type-2 papillary RCC

Yamasaki, Toshinari, Tran, Tram Anh T., Oz, Orhan K., Raj, Ganesh V., Schwarz, Roderich E., DeBerardinis, Ralph J., Zhang, Xuewu, Brugarolas, James

Journal:

Nature Reviews Urology (formerly Nature Clinical Practice Urology)

Year:

2011

Language:

english

File:

PDF, 999 KB

english, 2011

32

Stereotactic radiation therapy of renal cancer inferior vena cava tumor thrombus

Hannan, Raquibul, Margulis, Vitaly, Chun, Stephen G, Cannon, Nathan, Kim, D W Nathan, Abdulrahman, Ramzi E, Sagalowsky, Arthur, Pedrosa, Ivan, Choy, Hak, Brugarolas, James, Timmerman, Robert D

Journal:

Cancer Biology & Therapy

Year:

2015

Language:

english

File:

PDF, 661 KB

english, 2015

33

Clear cell renal cell carcinoma subtypes identified by BAP1 and PBRM1 expression

Joseph, Richard W., Kapur, Payal, Serie, Daniel J., Parasramka, Mansi, Ho, Thai H., Cheville, John C., Frenkel, Eugene, Parker, Alexander S., Brugarolas, James

Journal:

The Journal of Urology

Year:

2015

Language:

english

File:

PDF, 3.05 MB

english, 2015

34

Prospective evaluation of plasma levels of ANGPT2, TuM2PK, and VEGF in patients with renal cell carcinoma

Gayed, Bishoy A, Gillen, Jessica, Christie, Alana, Peña-Llopis, Samuel, Xie, Xian-Jin, Yan, Jingsheng, Karam, Jose A, Raj, Ganesh, Sagalowsky, Arthur I, Lotan, Yair, Margulis, Vitaly, Brugarolas, Jame

Journal:

Year:

2015

Language:

english

File:

PDF, 1.86 MB

english, 2015

35

Selective Efficacy of Temsirolimus on Bone Metastases in Chromophobe Renal Cell Carcinoma

Huelsmann, Lorel, Kim, D. Nathan W., Hannan, Raquibul, Watumull, Lori M., Brugarolas, James

Journal:

Clinical Genitourinary Cancer

Year:

2015

Language:

english

File:

PDF, 371 KB

english, 2015

36

Tumor Vascularity in Renal Masses: Correlation of Arterial Spin-Labeled and Dynamic Contrast-Enhanced Magnetic Resonance Imaging Assessments

Zhang, Yue, Kapur, Payal, Yuan, Qing, Xi, Yin, Carvo, Ingrid, Signoretti, Sabina, Dimitrov, Ivan, Cadeddu, Jeffrey A., Margulis, Vitaly, Muradyan, Naira, Brugarolas, James, Madhuranthakam, Ananth J.,

Journal:

Clinical Genitourinary Cancer

Year:

2015

Language:

english

File:

PDF, 2.95 MB

english, 2015

37

Loss of histone H3 lysine 36 trimethylation is associated with an increased risk of renal cell carcinoma-specific death

Ho, Thai H, Kapur, Payal, Joseph, Richard W, Serie, Daniel J, Eckel-Passow, Jeanette E, Tong, Pan, Wang, Jing, Castle, Erik P, Stanton, Melissa L, Cheville, John C, Jonasch, Eric, Brugarolas, James, P

Journal:

Modern Pathology

Year:

2015

Language:

english

File:

PDF, 1.67 MB

english, 2015

38

P21 Is a Critical CDK2 Regulator Essential for Proliferation Control in Rb-Deficient Cells

James Brugarolas, Roderick T. Bronson and Tyler Jacks

Journal:

The Journal of Cell Biology

Year:

1998

Language:

english

File:

PDF, 1.50 MB

english, 1998

39

SPIE Proceedings [SPIE SPIE Astronomical Telescopes + Instrumentation - San Diego, California, USA (Sunday 27 June 2010)] Space Telescopes and Instrumentation 2010: Optical, Infrared, and Millimeter Wave - ACCESS pointing control system

Brugarolas, Paul, Oschmann, Jr., Jacobus M., Clampin, Mark C., Alexander, James, Trauger, John, MacEwen, Howard A., Moody, Dwight, Egerman, Robert, Vallone, Phillip, Elias, Jason, Hejal, Reem, Camelo,

Year:

2010

Language:

english

File:

PDF, 5.04 MB

english, 2010

40

MP47-06 BRCA1 ASSOCIATED PROTEIN-1 (BAP-1) LOSS IN CCRCC: MOLECULAR CORRELATIONS AND VALIDATION AS A PROGNOSTIC FACTOR.

Kroeger, Nils, Kapur, Payal, Huang, Jiaoti, Belldegrun, Arie, Brugarolas, James, Pantuck, Allan

Journal:

The Journal of Urology

Year:

2015

Language:

english

File:

PDF, 161 KB

english, 2015

41

Intratumor Heterogeneity of Perfusion and Diffusion in Clear-Cell Renal Cell Carcinoma: Correlation With Tumor Cellularity

Yuan, Qing, Kapur, Payal, Zhang, Yue, Xi, Yin, Carvo, Ingrid, Signoretti, Sabina, Dimitrov, Ivan E., Cadeddu, Jeffrey A., Margulis, Vitaly, Brugarolas, James, Madhuranthakam, Ananth J., Pedrosa, Ivan

Journal:

Clinical Genitourinary Cancer

Year:

2016

Language:

english

File:

PDF, 1.27 MB

english, 2016

42

SPIE Proceedings [SPIE SPIE Optical Engineering + Applications - San Diego, California, United States (Sunday 25 August 2013)] Techniques and Instrumentation for Detection of Exoplanets VI - The Debris Disk Explorer: a balloon-borne coronagraph for observing debris disks

Roberts, Lewis C., Bryden, Geoffrey, Traub, Wesley, Unwin, Stephen, Trauger, John, Krist, John, Aldrich, Jack, Brugarolas, Paul, Stapelfeldt, Karl, Wyatt, Mark, Stuchlik, David, Lanzi, James, Shaklan,

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

43

Involvement of p53 and p21 in Cellular Defects and Tumorigenesis in Atm −/− Mice

Xu, Yang, Yang, Eva Marie, Brugarolas, James, Jacks, Tyler, Baltimore, David

Journal:

Molecular and Cellular Biology

Year:

1998

Language:

english

File:

PDF, 376 KB

english, 1998

44

Hepatic mTORC1 Opposes Impaired Insulin Action to Control Mitochondrial Metabolism in Obesity

Kucejova, Blanka, Duarte, Joao, Satapati, Santhosh, Fu, Xiaorong, Ilkayeva, Olga, Newgard, Christopher B., Brugarolas, James, Burgess, Shawn C.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.91 MB

english, 2016

45

Unsaturated Fatty Acids Stimulate Tumor Growth through Stabilization of β-Catenin

Kim, Hyeonwoo, Rodriguez-Navas, Carlos, Kollipara, Rahul K., Kapur, Payal, Pedrosa, Ivan, Brugarolas, James, Kittler, Ralf, Ye, Jin

Journal:

Year:

2015

Language:

english

File:

PDF, 1.78 MB

english, 2015

46

Multistep regulation of TFEB by MTORC1

Vega-Rubin-de-Celis, Silvia, Peña-Llopis, Samuel, Konda, Meghan, Brugarolas, James

Journal:

Year:

2017

Language:

english

File:

PDF, 644 KB

english, 2017

47

Multi-disciplinary surgical approach to the management of patients with renal cell carcinoma with venous tumor thrombus: 15 year experience and lessons learned

Gayed, Bishoy A., Youssef, Ramy, Darwish, Oussama, Kapur, Payal, Bagrodia, Aditya, Brugarolas, James, Raj, Ganesh, DiMaio, J. Michael, Sagalowsky, Arthur, Margulis, Vitaly

Journal:

Year:

2016

Language:

english

File:

PDF, 753 KB

english, 2016

48

Renal Cell Carcinoma With Pulmonary Metastasis and Metachronous Non-Small Cell Lung Cancer

Bowman, Isaac A., Pedrosa, Ivan, Kapur, Payal, Brugarolas, James

Journal:

Clinical Genitourinary Cancer

Year:

2017

Language:

english

File:

PDF, 4.93 MB

english, 2017

49

Discontinuing VEGF-targeted Therapy for Progression Versus Toxicity Affects Outcomes of Second-line Therapies in Metastatic Renal Cell Carcinoma

De Velasco, Guillermo, Xie, Wanling, Donskov, Frede, Albiges, Laurence, Beuselinck, Benoit, Srinivas, Sandy, Agarwal, Neeraj, Lee, Jae Lyun, Brugarolas, James, Wood, Lori A., Rha, Sun-young, Kollmanns

Journal:

Clinical Genitourinary Cancer

Year:

2017

Language:

english

File:

PDF, 787 KB

english, 2017

50

Hypoxia-inducible factor-1α activates insig-2 transcription for degradation of HMG CoA reductase in the liver

Hwang, Seonghwan, Nguyen, Andrew D., Jo, Youngah, Engelking, Luke J., Brugarolas, James, DeBose-Boyd, Russell A.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 9.06 MB

english, 2017